BIO 3400 Scioli
Summer II 1999

Objectives / Review for Exam III - new material, part 1

  • Quantitative genetics
    1. quantitative versus qualitative traits
    2. phenotypic variance
      1. Vp = Vg + Ve
      2. Vp is the total phenotypic variance
      3. Vg is the total genotypic variance
      4. Ve is the total environmental variance
    3. genetic variance
      1. Vg = Va + Vd + Vi
      2. Va is the variance due to additive (polygenic) loci
      3. Vd is the variance due to dominance relationships
      4. Vi is the variance due to epistatis or other forms of genetic interaction
    4. heritability
      1. narrow-sense heritability
        1. hn = Va / Vp
        2. hn = robs / rexp
          1. robs is the observed correlation between relatives for expression of a phenotypic trait
          2. rexp is the expected correlation between relatives for expression of that phenotypic trait
      2. broad-sense heritability
        1. Hb = Vg / Vp
    5. Much of the study of quantitative inheritance was initiated in the period from 1900 - 1920, a time when Mendelism was not universally accepted. Francis Galton, Karl Pearson and other Biometricians were responsible for developing statistical techniques to analyze data from observations on small, interindividual differences.

    This is not intended to be an exhaustive transcript of everything discussed in class; however, major topics not listed here will not be covered on the exam. It is intended as a guide to help in your preparation for the exam. When in doubt about the details, look first to your class notes, then check out the index at the back of your textbook(s).


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